RESUMO
La candidiasis cutánea congénita es una infección poco frecuente, producida por Candida spp., que se desarrolla en la primera semana de vida. Su curso es habitualmente benigno y autolimitado, aunque existen casos graves de infección diseminada. Se presentan 2 casos de recién nacidos con eritema generalizado y rápida evolución a exantema papulopustular. En los cultivos de las lesiones se aisló Candida albicans. Ambos recibieron tratamiento tópico y presentaron una evolución favorable y sin complicaciones. Se revisan los factores de riesgo, la fisiopatología, las formas de presentación y la evolución de la candidiasis cutánea congénita (AU)
Congenital cutaneous candidiasis is an uncommon infection due to Candida spp. which develops within the first week of life. It has usually a benign and self-limited course although there are serious cases of systemic disease. We review the cases of two newborns with disseminate erythema present at birth. Both of them showed a rapid evolution to a papulo-pustular rash. Candida Albicans was isolated in cultures of the cutaneous lesions. After topical treatment, newborns presented a favourable outcome without any complications. Risk factors, physiopathology, clinical presentation and outcome of congenital cutaneous candidiasis are revised (AU)
Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Candidíase Cutânea/diagnóstico , Candida albicans/isolamento & purificação , Candidíase Cutânea/tratamento farmacológico , Candidemia/prevenção & controle , Doenças do Recém-Nascido/diagnóstico , Exantema/etiologia , Corioamnionite , Fatores de RiscoRESUMO
Two new cases of type B congenital interruption of the aortic arch are described. Both had other congenital cardiovascular malformations as well as absence of the thymus and parathyroids. They were newborn male and female, their parents were young and healthy, admitted in our institution because of feeding difficulty, respiratory distress and cyanosis with signs of heart failure. Both were diagnosed at necropsy. According to the site of the interruption of the aortic arch, three types (A, B and C) of absence of the aortic arch are recognized. In our patients as in the majority of reported cases, the interruption of the aortic arch was associated with patent ductus arteriosus, ventricular septal defect and atrial septal defect, and other cardiovascular anomalies. The association of Di George syndrome with cardiovascular anomalies is commented.
